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Ernest Y. Lee, MD, PhD
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NETs generate structured antimicrobial peptide-nucleosome immune complexes with inter-DNA spacings optimal for TLR9 activation
Date
May 9, 2019
11:15 AM — 12:15 PM
Event
2019 Society of Investigative Dermatology Annual Meeting
Location
Chicago, Illinois
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NETs generate immune complexes to amplify TLR9-based inflammation in psoriasis
LL37 antimicrobial peptides amplify inflammation in psoriasis by assembling into protofibril scaffolds that present ordered nucleic acids to TLR9 and TLR3
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