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Ernest Y. Lee, MD, PhD
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LL37 antimicrobial peptides amplify inflammation in psoriasis by assembling into protofibril scaffolds that present ordered nucleic acids to TLR9 and TLR3
Date
May 30, 2019
6:00 PM — 7:00 PM
Event
2019 National Psoriasis Foundation Cure Symposium
Location
Seattle, Washington
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NETs generate structured antimicrobial peptide-nucleosome immune complexes with inter-DNA spacings optimal for TLR9 activation
Host defense peptides amplify TLR9-mediated inflammation in autoimmune diseases by scaffolding dsDNA into spatially-periodic nanocrystals
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